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. Author manuscript; available in PMC: 2017 Aug 31.
Published in final edited form as: Bone. 2016 Jul 12;91:64–74. doi: 10.1016/j.bone.2016.07.006

Fig. 2.

Fig. 2

qPCR analysis of Jag1-null bones. Gene expression of Notch pathway components (A) Jag1, (B) Hes1 and (C) Hey1, osteogenic genes (D) osteocalcin (Ocn), (E) osterix (Osx) and (F) collagen type-I (Col1a1) and pro-osteoclastogenesis genes (G) receptor activator of nuclear factor kappa-B ligand (RANKL), (H) osteoprotegerin (Opg) and (I) tartrate-resistant acid phosphatase (TRAP). For all analyses, data are presented as fold change expression to each genotype's respective whole bone (Prx1-Cre;Jag1f/f or Col2.3-Cre;Jag1f/f) calculated using the formula 2−ΔΔC(t) (*p < 0.050, #p < 0.100).