Table 3. The effect of diabetes and retinopathy on impaired cognitive function by multivariable logistic analysis.
Variables | Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|
OR | OR | OR | ||||
(95%confidence interval) | P | (95%confidence interval) | P | (95%confidence interval) | P | |
Cognitive impairment | ||||||
DM | 0.84(0.31,2.31) | 0.74 | 0.82(0.29,2.30) | 0.709 | 0.85(0.30,2.39) | 0.76 |
DM and Retinopathy | 2.09(1.11,3.92) | 0.022 | 2.19(1.13,4.26) | 0.021 | 2.15(1.10,4.20) | 0.03 |
Executive dysfunction | ||||||
DM | 1.78(0.73,4.35) | 0.206 | 1.71(0.68,4.31) | 0.259 | 1.79(0.71,4.53) | 0.22 |
DM and Retinopathy | 2.89(1.55,5.37) | 0.001 | 2.88(1.51,5.52) | 0.001 | 2.82(1.46,5.42) | 0.002 |
Impaired immediate memory | ||||||
DM | 1.85(0.78,4.42) | 0.164 | 1.74(0.71,4.22) | 0.22 | 1.86(0.76,4.54) | 0.17 |
DM and Retinopathy | 2.16(1.15,4.06) | 0.016 | 2.17(1.13,4.20) | 0.02 | 2.05(1.05,3.98) | 0.04 |
Impaired delayed memory | ||||||
DM | 1.12(0.43,2.95) | 0.81 | 1.03(0.40,2.79) | 0.954 | 1.04(0.38,2.82) | 0.94 |
DM and Retinopathy | 0.71(0.35,1.44) | 0.347 | 0.59(0.59,1.28) | 0.169 | 0.57(0.27,1.21) | 0.14 |
Impaired language ability | ||||||
DM | 1.93(0.77,4.82) | 0.159 | 1.91(0.72,5.09) | 0.196 | 1.81(0.64,5.12) | 0.19 |
DM and Retinopathy | 1.68(0.87,3.23) | 0.121 | 1.86(0.93,3.74) | 0.081 | 1.81(0.90,3.65) | 0.1 |
Impaired visuospatial skill | ||||||
DM | 1.34(0.60,2.99) | 0.474 | 1.50(0.64,3.50) | 0.347 | 1.508(0.65,3.52) | 0.34 |
DM and Retinopathy | 2.37(1.32,4.22) | 0.004 | 2.60(1.41,4.79) | 0.002 | 2.58(1.40,4.77) | 0.002 |
Model 1: age, sex, education level, BMI, DM and retinopathy; Model 2:, Model 1 plus serum albumin level, sodium level, total cholesterol level, high-sensitivity C-reactive protein level, and residual kidney function; Model3: Model 2 plus cerebrovascular disease; Abbreviations: OR: odd ratio.