Table 2: Serum conversion to HBsAg in HBsAg-tg mice and in non-transgenic mice

				Dose 3						Dose 5						Dose 10
Mouse		Isotype		Micea		Ab (+)		%		Mice		Ab (+)		%		Mice		Ab (+)		%
Tg		IgG1		11		1		9		8		8		100		4		4		100
		IgG2a		11		0		0		8		5		63		4		3		75
Ntg		IgG1		9		9		100		6		6		100		3		3		100
		IgG2a		9		9		100		6		6		100		3		3		100

^aAfter the 3th, 5th, and 10th doses, three to four mice were sacrificed and spleen cells isolated for T-cells response evaluation