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. 2017 Aug 31;12(8):e0183833. doi: 10.1371/journal.pone.0183833

Table 5. Risk factors for cataract formation.

Univariate and multivariate risk factor analysis.

95% CI for hazard ratio
HR Lower Upper p value
Univariate analysis
Treatment dose ≥90 Gy 0.0137*
Posterior tumor margin
    1–2 DD from disc or foveola 1.6 0.6 4.3 0.339
    posterior to the equator 1.4 0.6 3.4 0.408
    anterior to the equator 3.3 1.3 8.3 0.013*
Dtd 1.0 1.0 1.1 0.055
Dtf 1.04 1.0 1.1 0.087
Pre-existing cataract 0.6 0.3 1.0 0.071
Pre-existing cataract f.e. 0.5 0.3 1.0 0.045*
Multivariate analysis
Posterior tumor margin
    1–2 DD from disc or foveola 1.6 0.6 4.3 0.339
    posterior to the equator 1.4 0.6 3.4 0.408
    anterior to the equator 3.3 1.3 8.3 0.013*

Table 5: showing the results of the univariate and multivariate risk factor analysis for cataract formation. Treatment dose ≥90 Gy = total treatment dose to the tumor apex ≥ 90 Gray; f.e. = fellow eye; Dtd = tumor distance to disc; Dtf = tumor distance to foveola; CI = confidence interval; HR = hazard ratio; Gy = Gray; DD = disc diameter; 1–2 DD to disc or foveola = 1–2 disc diameter distance of the posterior tumor margin to the optic disc or the center of the macula

* values marked by "*" showed to be statistically significant.