Table 5. Risk factors for cataract formation.
95% CI for hazard ratio | ||||
---|---|---|---|---|
HR | Lower | Upper | p value | |
Univariate analysis | ||||
Treatment dose ≥90 Gy | 0.0137* | |||
Posterior tumor margin | ||||
1–2 DD from disc or foveola | 1.6 | 0.6 | 4.3 | 0.339 |
posterior to the equator | 1.4 | 0.6 | 3.4 | 0.408 |
anterior to the equator | 3.3 | 1.3 | 8.3 | 0.013* |
Dtd | 1.0 | 1.0 | 1.1 | 0.055 |
Dtf | 1.04 | 1.0 | 1.1 | 0.087 |
Pre-existing cataract | 0.6 | 0.3 | 1.0 | 0.071 |
Pre-existing cataract f.e. | 0.5 | 0.3 | 1.0 | 0.045* |
Multivariate analysis | ||||
Posterior tumor margin | ||||
1–2 DD from disc or foveola | 1.6 | 0.6 | 4.3 | 0.339 |
posterior to the equator | 1.4 | 0.6 | 3.4 | 0.408 |
anterior to the equator | 3.3 | 1.3 | 8.3 | 0.013* |
Table 5: showing the results of the univariate and multivariate risk factor analysis for cataract formation. Treatment dose ≥90 Gy = total treatment dose to the tumor apex ≥ 90 Gray; f.e. = fellow eye; Dtd = tumor distance to disc; Dtf = tumor distance to foveola; CI = confidence interval; HR = hazard ratio; Gy = Gray; DD = disc diameter; 1–2 DD to disc or foveola = 1–2 disc diameter distance of the posterior tumor margin to the optic disc or the center of the macula
* values marked by "*" showed to be statistically significant.