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. Author manuscript; available in PMC: 2017 Aug 31.
Published in final edited form as: Adv Drug Deliv Rev. 2017 Jun 10;113:177–200. doi: 10.1016/j.addr.2017.06.002

Figure 5.

Figure 5

Molecular transport across normal BBB. In the healthy BBB, there are many mechanisms by which endogenous substances are able to migrate from blood to brain. In addition to simple diffusion, entry mechanisms involve channels, carriers, and receptors.