Table 4.
Odds ratios for preterm birth by quartile of maternal urinary perchlorate concentration in the study population of pregnant women from San Diego County 2000–2003
| Both sexes
|
Males
|
Females
|
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gro up |
Per c qua rt. |
Cas es |
Co nt |
O R1 |
95 % CI L |
95 % CI U |
p- tre nd |
Cas es |
Co nt |
O R1 |
95 % CI L |
95 % CI U |
p- tre nd |
Cas es |
Co nt |
O R1 |
95 % CI L |
95 % CI U |
p- tre nd |
| All preterm births: | |||||||||||||||||||
| 1 | 36 | 452 | 1.00 | Ref | 21 | 218 | 1.00 | Ref | 15 | 234 | 1.00 | Ref | |||||||
| 2 | 33 | 458 | 0.86 | 0.51 | 1.45 | 17 | 220 | 0.77 | 0.38 | 1.56 | 16 | 238 | 0.94 | 0.43 | 2.04 | ||||
| 3 | 43 | 447 | 1.09 | 0.64 | 1.85 | 21 | 219 | 0.86 | 0.41 | 1.82 | 22 | 228 | 1.30 | 0.60 | 2.82 | ||||
| 4 | 46 | 442 | 1.11 | 0.64 | 1.92 | 0.72 | 26 | 217 | 1.14 | 0.53 | 2.45 | 0.73 | 20 | 225 | 1.06 | 0.47 | 2.38 | 0.90 | |
| Preterm ≥2500 g: | |||||||||||||||||||
| 1 | 19 | 469 | 1.00 | Ref | 9 | 230 | 1.00 | Ref | 10 | 239 | 1.00 | Ref | |||||||
| 2 | 22 | 469 | 1.09 | 0.56 | 2.11 | 12 | 225 | 1.39 | 0.54 | 3.57 | 10 | 244 | 0.86 | 0.33 | 2.22 | ||||
| 3 | 33 | 457 | 1.53 | 0.79 | 2.99 | 19 | 221 | 1.82 | 0.69 | 4.80 | 14 | 236 | 1.22 | 0.47 | 3.13 | ||||
| 4 | 37 | 451 | 1.84 | 0.91 | 3.72 | 0.09 | 24 | 219 | 3.03 | 1.09 | 8.40 | 0.03 | 13 | 232 | 1.07 | 0.39 | 2.89 | 0.90 | |
| Preterm <2500 g: | |||||||||||||||||||
| 1 | 17 | 471 | 1.00 | Ref | 12 | 227 | 1.00 | Ref | 5 | 244 | 1.00 | Ref | |||||||
| 2 | 11 | 480 | 0.62 | 0.27 | 1.39 | 5 | 232 | 0.37 | 0.12 | 1.12 | 6 | 248 | 1.11 | 0.30 | 4.08 | ||||
| 3 | 10 | 480 | 0.57 | 0.23 | 1.39 | 2 | 238 | 0.16 | 0.03 | 0.79 | 8 | 242 | 1.44 | 0.40 | 5.21 | ||||
| 4 | 9 | 479 | 0.42 | 0.16 | 1.06 | 0.07 | 2 | 241 | 0.12 | 0.02 | 0.61 | 0.01 | 7 | 238 | 1.06 | 0.28 | 3.97 | 0.94 | |
Abbreviations: CIL, lower confidence interval; CIU, upper confidence interval; Cont, controls; OR, odds ratio; Perc quart, maternal urinary perchlorate concentration quartile unadjusted for urinary creatinine concentrations (cut-off points are 3.94, 6.50, and 10.0 µg/L); Ref, Reference category
Adjusted for creatinine (log10), maternal age, maternal weight, race, (and sex, for analyses of both sexes)