Table A4.
Results of the mediation analysis of maternal serum total thyroxine (T4) on the association between maternal urine perchlorate and birthweight in male infants (n=862) in the study population of pregnant women from San Diego County 2000–20031
| Model | Dependent variable |
Independent variables |
β | SE | p-value |
|---|---|---|---|---|---|
| MODEL 1 | T4 | Log10 perchlorate | −0.73 | 0.22 | 0.0008 |
| MODEL 22 | Birthweight | Log10 perchlorate | 133.6 | 60.4 | 0.03 |
| T4 | −22.1 | 9.4 | 0.02 | ||
| MODEL 3 | Birthweight | Log10 perchlorate | 149.8 | 60.2 | 0.01 |
1
All models adjusted for urinary creatinine (log10). All models include the same 862 male subjects with information on perchlorate, creatinine, and maternal T4
2
This model includes both log10 perchlorate and serum T4