Table 3.
FLG variants
|
|||
---|---|---|---|
FLG probe ID | Yes (n = 6) (haploinsufficiency) |
No (n = 88) (wild-type) |
P value |
Sense transcripts | |||
A_24_P51322, Median (IQR) | −0.97 (0.81) | 0.16 (1.14) | 0.007 |
A_32_P387648, Median (IQR) | −0.39 (0.45) | 0.09 (0.97) | 0.052 |
A_33_P3261328, Median (IQR) | 0.09 (0.96) | −0.01 (0.60) | 0.799 |
Antisense transcripts | |||
A_21_P0014075, Median (IQR) | 0.09 (0.41) | 0.02 (0.78) | 0.740 |
A_33_P3296200, Median (IQR) | −0.43 (0.47) | 0.09 (0.93) | 0.031 |
FLG, filaggrin; ID, identification; IQR, interquartile range.
FLG expression values presented as normalized log-base 2 intensities.