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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Clin Exp Allergy. 2017 Jun 19;47(9):1185–1192. doi: 10.1111/cea.12956

Table 5.

Estimates of area under the receiver operating characteristic curve of models predicting eczema at 3-, 6-, and 12-months of age

Eczema at 3
months (n = 88)
Eczema at 6
months (n = 83)
Eczema at 12
months (n = 80)

Variables AUC (95% CI) AUC (95% CI) AUC (95% CI)
Model 1 A_24_P51322 (sense transcript) 0.72 (0.53 – 0.91) 0.71 (0.56 – 0.85) 0.66 (0.48 – 0.83)
Model 2 A_24_P51322 + Sex 0.87 (0.78 – 0.96) 0.76 (0.64 – 0.88) 0.72 (0.55 – 0.89)
Model 3 A_24_P51322 + FLG variants 0.74 (0.54 – 0.93) 0.72 (0.57 – 0.86) 0.66 (0.49 – 0.84)
Model 4 A_24_P51322 + Sex + FLG variants 0.88 (0.79 – 0.97) 0.76 (0.64 – 0.89) 0.72 (0.55 – 0.89)
Model 5 A_21_P0014075 (antisense transcript) 0.63 (0.45 – 0.80) 0.61 (0.45 – 0.76) 0.60 (0.43 – 0.76)
Model 6 A_21_P0014075 + Sex 0.87 (0.78 – 0.95) 0.72 (0.59 – 0.85) 0.71 (0.56 – 0.86)
Model 7 A_21_P0014075 + FLG variants 0.78 (0.62 – 0.94) 0.73 (0.58 – 0.88) 0.71 (0.55 – 0.87)
Model 8 A_21_P0014075 + Sex + FLG variants 0.91 (0.84–0.98) 0.77 (0.63 – 0.90) 0.75 (0.61 – 0.90)

FLG, filaggrin; AUC, area under the receiver operating characteristic curve; CI, confidence interval