Skip to main content
. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Clin Exp Allergy. 2017 Jun 9;47(9):1214–1222. doi: 10.1111/cea.12949

Figure 1.

Figure 1

Increase in DARC expression in alveolar epithelial cells in wild type mice 24 hours and 7 days following house dust mite (HDM) challenge. (A) Mice were challenged with 15 intranasal instillations of HDM over three weeks and evaluated at 24 hours and 7 days following the final instillation. DARC (B) mRNA and (C) protein expression was increased in lung homogenates at both 24 hours and 7 days. Lung tissue sections were stained using an antibody for DARC (red) and Club Cell Secretory Protein (CCSP, green), as a marker of airway epithelial cell co-localization. Data are presented as mean ± SEM of 8–9 mice/group. ANOVA with Tukey post-hoc comparisons: * p < 0.05 and $ p ≤ 0.08 vs respective PBS.