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. 2017 Aug 31;7:10150. doi: 10.1038/s41598-017-07861-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The frequency of myogenic contractions is significantly higher in Transition Zone specimens from men with BPH compared to age and volume matched controls. Frequency distribution histograms of BPH diagnosed men within the patient cohort by (A) Age and (B) Prostate Volume. The average (C,F) basal tension (mN), (D,G) amplitude and (D,H) frequency of spontaneous contractions within the TZ of men with clinically diagnosed BPH compared to age (B,C,D) and prostate volume (F,G,H) matched controls (Student’s unpaired t-test, n = 9, * indicates p < 0.05, *** indicates p < 0.001).