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. 2017 Aug 31;7:10160. doi: 10.1038/s41598-017-07764-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Results of the analyses on gray matter glucose metabolism. T-values of the voxelwise regression analysis between the z-score maps of the 186 controls (corrected for education) and age were superimposed on brain surface views (a). Mean w-score values of the expert meditators corrected for age and education and using the elderly control group as the reference (b), and clusters of interest showing significantly higher values in the expert meditators (voxel-level p < 0.001 and FWE-corrected cluster-level p < 0.05) (c) were superimposed on brain surface views. Glucose metabolism residuals in the 3 clusters of interest were plotted in the elderly expert meditators (orange) and in the controls (blue) of the elderly control group (d; residuals are corrected for age and education); of the entire control group against age (e; residuals are corrected for education). VMPF-ACC: ventromedial prefrontal and anterior cingulate cortex; TP: temporo-parietal.