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. 2017 Aug 31;7:10213. doi: 10.1038/s41598-017-10222-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Illustration of lentiviral vectors used in the study. (a) The diagram of predicted CpG island in the 2.2 kb A2UCOE using MethPrimer program (www.urogene.org) and corresponding UCOE fragments used in the study. The location of the exon1 of CBX3 is indicated. (b) Illustration of the lentiviral vector constructs. LTR: long-terminal repeat; SFFV: Spleen focus-forming virus LTR; CMV: Cytomegalovirus; mutWpre: mutated Woodchuck hepatitis posttranscriptional regulatory element.