Table 1.
Summary of chemicals associated with increased mammary gland tumors in rodent models
| Chemicals | Concentration in smoke of nonfilter cigarette | IARC group |
|---|---|---|
| benzo(a)pyrene | 20–40 ng | 2A |
| toluidine | 30-337 ng | 2B |
| 4-aminobiphenyl N-heterocylic amines | 25–260 | 1 |
| IQ | 0.3 | 2A |
| hydrazine | 24–43 | 2B |
| PhIP | 11–23 | 2B |
| isoprene | 450–1000 I g | 2B |
| benzene | 20–70 I g | 1 |
| styrene | 10 I g | 2B |
| nitromethane | 0.5–0.6 I g | 2B |
| nitrobenzen | 25 Ig | 2B |
| acrylamide | Present | 2B |
| acrylonitrile | 3–15 I g | 2A |
| vinyl chloride | 11–15 I g | 1 |
| ethylene oxide | 7 I g | 1 |
| propylene oxide | 0-100 ng | 2B |
| dibenz(a,h)anthracene | 4 ng | 2A |
| N-nitrosamines | ||
| N-nitrosonornicotine | 120–3700 ng | 2B |
| N-nitrosodimethylamine | 2–1000 ng | 2A |
| N-nitrosodiethylamine | ND-2.8 ng | 2A |
| 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone | 80–770 ng | 2B |
IQ: 3-methylimidazo[4,5-fjquinoline, PhIP: 2-Amino-1-Methyl-6-Phenylimidazo 4 5-b pyridine