Table 1.
Clinical and neuropathological characteristics of autopsy cases. No significant differences were detected between patients and control groups for the listed variables (PD Parkinson disease, AD Alzheimer disease, SEM standard error of the mean, PMI post-mortem interval [hours from death to freezing of specimen])
| Diagnosis | Brain area | Number | Age (years ± SEM) | Sex (male + female) | PMI (hours ± SEM) |
|---|---|---|---|---|---|
| PD | Putamen | 10 | 81.4 ± 6.7 | 7 + 3 | 14:58 ± 7:20 |
| Controls | Putamen | 10 | 76.4 ± 9.1 | 7 + 3 | 16:26 ± 2:54 |
| PD | Caudate nucleus | 10 | 81.4 ± 6.7 | 7 + 3 | 14:58 ± 7:20 |
| Controls | Caudate nucleus | 10 | 76.4 ± 9.1 | 7 + 3 | 16:26 ± 2:54 |
| PD | Substantia nigra | 16 | 76.3 ± 6.4 | 12 + 4 | 12:37 ± 7:46 |
| Controls | Substantia nigra | 18 | 73.4 ± 12.5 | 12 + 6 | 14:08 ± 7:18 |
| PD | Cerebellum | 10 | 76.2 ± 5.4 | 7 + 3 | 22:50 ± 20:45 |
| Controls | Cerebellum | 10 | 78.7 ± 8.9 | 5 + 5 | 24:53 ± 22:09 |
| AD | Frontal cortex | 25 | 76.4 ± 11.9 | 12 + 13 | 5:30 ± 1:40 |
| Controls | Frontal cortex | 20 | 76.3 ± 11.8 | 9 + 11 | 6:42 ± 1:32 |
| AD | Hippocampus | 25 | 74.7 ± 11.3 | 13 + 12 | 8:01 ± 4:52 |
| Controls | Hippocampus | 20 | 57.1 ± 11.8 | 10 + 10 | 9:10 ± 4:48 |