Table 1.

Comparison of different criteria for diagnosis of multiple sclerosis (MS)

				Sensitivity (%)	Specificity (%)	Accuracy (%)
				(95% CI)	(95% CI)	(95% CI)
McDonalds DIS Criterion				96	40	80
	Positive	Negative	Total	(80––100)	(12–74)	(63–92)
MS	24	1	25
SVD	6	4	10
Total	31	4
VIL+ 45%				100	80	94
	Positive	Negative	Total	(86–100)	(44–97)	(81–99)
MS	25	0	25
SVD	2	8	10
Total	27	8
VIL+ 60%				96	90	94
	Positive	Negative	Total	(80–100)	(56–100)	(81–99)
MS	24	1	25
SVD	1	9	10
Total	25	10
Rule of Six				100	70	91
	Positive	Negative	Total	(86–100)	(35–93)	(77–98)
MS	25	0	25
SVD	3	7	10
Total	28	7

CI confidence interval, SVD small vessel disease, DIS dissemination in space, s vein in lesion