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. 2017 Aug 31;7:10188. doi: 10.1038/s41598-017-10684-5

Figure 5.

Figure 5

IL-6 signal pathway in PBL-1. (a) Western blot analysis of IL-6 signal-associated proteins. (b) Effect of inhibitors for Jak/STAT and PI3K/Akt/mTOR pathways on PBL-1 by XTT assay. Cell proliferation ratio (%) in XTT assay and the concentration of each drug are indicated on the vertical and horizontal axes. All inhibitors were added to medium supplemented with 5 ng/mL IL-6. The error bars represent the standard deviation of the measurements. (c) The IL-6 signal pathway in PBL-1. Inhibitors and the IC50 are indicated at their targets.