Table 2.
Single-marker-based analyses of 4 SNPs that were genotyped in samples (additive model).
| CHR | SNP | BP | Effect allele | Other allele | Discovery (N = 1,488) | Combined Sample (N = 4,206) | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95%CI | P | OR | 95%CI | P | |||||
| 7 | rs1800796 | 22726627 | G | C | 0.79 | [0.62,0.99] | 0.0427 | 0.84 | [0.73,0.98] | 0.0228 |
| 7 | rs2069837 | 22728408 | G | T | 1.08 | [0.83,1.39] | 0.5652 | 1.02 | [0.87,1.20] | 0.7794 |
| 19 | rs6508976 | 41348769 | G | T | 1.03 | [0.84,1.26] | 0.7539 | 0.99 | [0.88,1.13] | 0.9292 |
| 19 | rs1800470 | 41353016 | G | A | 1.37 | [1.12,1.68] | 0.0023 | 1.26 | [1.11,1.42] | 0.0004 |
The significant SNP is indicated in bold. The P value threshold used in the combined sample was 0.05/2 = 0.025.