Table 2.
Clinical characteristics of participants included in the study.
| IBD | UC | CD | Healthy control | |
|---|---|---|---|---|
| Number patients | 192 | 122 | 70 | 137 |
| Female/Male | 110/82 | 73/49 | 44/26 | 76/61 |
| Age at entry (Mean ± SE), years | 38.81 ± 1.02 | 37.76 ± 1.12 | 40.75 ± 1.98 | 45.36 ± 1.83 |
| Extension of disease | ||||
| Proctitis | 26 | |||
| Left-sided colitis | 30 | |||
| Extensive | 66 | |||
| Location of CD | ||||
| Ileon | 17 | |||
| Colon | 34 | |||
| Ileocolonic | 19 | |||
| Disease behavior, CD | ||||
| Inflammatory | 62 | |||
| Stricturing | 7 | |||
| Penetrating | 1 | |||
| Severity of the previous episodea | ||||
| Inactive | 30 | 15 | ||
| Mild | 28 | 18 | ||
| Moderate | 38 | 26 | ||
| Severe | 26 | 11 | ||
| Medication at endoscopyb | ||||
| No medication | 24 | 18 | 6 | |
| 5-ASA | 125 | 86 | 39 | |
| Corticosteroids | 47 | 33 | 14 | |
| Azathioprine | 54 | 24 | 30 | |
| Biologics (Infliximab) | 17 | 4 | 13 | |
| Intestinal resection surgery | 32 | 16 | 16 | |
aSeverity according Mayo endoscopic subscore in UC and according to SES in CD (0 = Inactive; 1 = Mild; 2 = Moderate; 3 = Severe). bSome patients received combined therapies.