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. 2017 Aug 2;36(17):2473–2487. doi: 10.15252/embj.201797397

Figure 4. Analogy between cancer immunity and protective mechanism in brain.

Figure 4

Analogy between cancer and AD. Because of cancer immunity mechanisms, it generally takes cancer stem cells more than a decade to develop pathological cancer. Human brains may possess similar protective mechanisms for AD, which can explain why it takes Aβ amyloidosis decades to induce neurodegeneration, whose identification may improve animal models and protective medications.