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. 2017 Jul 3;36(17):2510–2528. doi: 10.15252/embj.201696089

Figure 8. YAP expression and Skp2 expression are positively correlated in breast cancer patients.

Figure 8

  1. Scatter plot comparing Skp2 and YAP mRNA expression from breast cancer patient microarrays (n = 159 for GSE1456; n = 508 for GSE25066; n = 198 for GSE7390; r = Pearson's correlation coefficient). See Fig EV5A.
  2. Heatmap analysis using cBioPortal showing Skp2 and YAP target gene sets in breast invasive carcinoma patients. Data are presented as fold change in Log2.
  3. Immunohistochemical analysis of tissues used for microarrays (TMA) from breast cancer patients using YAP‐ and Skp2‐specific antibodies. Representative images and statistical analysis of the tissue microarray data are shown. P‐value was calculated using the chi‐square test. Scale bars: 50 μm.