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. 2017 Jun 22;18(9):1559–1571. doi: 10.15252/embr.201744102

Figure 1. The kinetochore network across 90 eukaryotic lineages.

Figure 1

Presences and absences (“phylogenetic profiles”) of 70 kinetochore proteins in 90 eukaryotic species. Top: Phylogenetic tree of the species in the proteome set, with colored areas for the eukaryotic supergroups. Left side: Kinetochore proteins clustered by average linkage based on the pairwise Pearson correlation coefficients of their phylogenetic profiles. Protein names have the same colors if they are members of the same complex. Proteins inferred to have been present in LECA are indicated (●). The orthologous sequences (including sets of APC/C subunits, NAG, RINT1, HORMAD, Nup106, Nup133, Nup160) are available as fasta files in Dataset EV1, allowing full usage of our data for further evolutionary cell biology investigations.