Figure 7. Phosphorylation of Dbf4 is integral to the timely destruction of SC proteins.

• A, B
  Strains were induced to synchronously enter meiosis. At 6 h, β‐estradiol was added to induce production of Cdc5. Cells were harvested at the indicated time points, and proteins were detected as in Fig 1B. dbf4‐4A encodes four Ser/Thr to Ala mutations (S318A, S319A, S374A, T375A).
• C
  Schematic model of how the CDK‐DDK‐Polo axis facilitates the transition from meiotic prophase I to metaphase I. dep., dependent; pro, prophase I; meta, metaphase I; ana, anaphase I; HR, homologous recombination.

Source data are available online for this figure.