Table 1.

Clinicopathological features of 44 bladder cancer patients and the expression of circHIPK3 and miR‐558

Parameters	Group	Cases	circHIPK3 expression				P‐value	miR‐558 expression				P‐value
			Low	%	High	%		Low	%	High	%
Gender	Male	27	21	78	6	22	0.7141	5	19	22	81	0.9418
	Female	17	14	82	3	18		3	18	14	82
Age at surgery	< 55	21	17	81	4	19	0.6788	4	19	17	81	0.8869
	≥ 55	23	18	78	5	22		4	17	19	83
Pathological stage	pTa‐T1	11	4	36	7	64	< 0.0001	5	45	6	55	0.0068
	pT2‐T4	33	31	94	2	6		3	9	30	91
Grade	Low	13	7	54	6	46	0.0062	6	46	7	54	0.0018
	High	31	28	90	3	10		2	6	29	94
Lymph node metastasis	Absent	27	19	70	8	30	0.0479	7	26	20	74	0.0933
	Present	17	16	94	1	6		1	6	16	94
Vascular invasion	Absent	29	20	69	9	31	0.0156	7	24	22	76	0.1544
	Present	15	15	100	0	0		1	7	14	93
Total		44	35	80	9	20		8	18	36	82

P < 0.05 represents statistical significance (Chi‐square test).