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. 2017 Aug 22;2(8):4820–4827. doi: 10.1021/acsomega.7b01054

Table 2. Preparative Scale Production of AO Metabolites Using ecoAOa.

substrate mM –1 cm –1 metabolite mM–1 cm –1 % yield
zoniporide ε315 6.48 ± 0.04 2-oxo-zoniporide ε280 5.48 ± 0.15 10
DACA ε358 10.48 ± 0.09 DACA-acridone ε409 9.24 ± 0.07 25
zaleplon ε333 7.04 ± 0.03 5-oxo-zaleplon ε330 7.70 ± 0.26 10
O6-BG ε282 9.10 ± 0.05 8-oxo-O6-BG ε290 9.50 ± 0.22 12
a

All extinction coefficients were determined in buffer (pH 7.4) using an Agilent 8453 UV–vis spectrophotometer (Agilent Technologies, Santa Clara, CA). The error is reported as the SD for duplicate measurements.