Table 3.
Comparison between glucose biosensors based on mediated (MET) and direct electron transfer (DET). List of abbreviations: 1,1′-dimethylferrocene (DMFc), 1,2-diaminobenzene (p-DAB), 4-aminophenol (4-APh), 4-mercaptobenzoic acid (4-MBA), Corynascus thermophilus cellobiose dehydrogenase (CtCDH), Corynascus thermophilus cellobiose dehydrogenase C291Y mutant (CtCDH C291Y), ferrocene-COOH (Fc-COOH), glassy carbon electrode (GC), glucose oxidase (GOx), glutaraldehyde (GA), gold (Au), gold nanoparticles (AuNPs), osmium (bpy)2poly (1-vinylimidazole) (PVI-Os), Prussian Blue (PB), screen-printed carbon electrode (SPCE), single walled carbon nanotubes (SWCNTs), titanium nanotubes (TiNTs).
| Modified Electrode | Eapp/V vs. Ag|AgClsat | Linear Range/mM | LOD/μM | Sensitivity/μA mM−1 cm−2 | Stability | Reference |
|---|---|---|---|---|---|---|
| (GOx/Au/pDAB)-PB/AuNPs/TiNTs (1st generation) | −0.35 | 0.01–0.70 | 3.2 | 248.0 | >90% after 1 month | [49] |
| GOx-GA/PB/Pt (1st generation) | −0.05 | 0.01–1 | 5 | 80.0 | 83.3% after 23 days | [50] |
| GOx/PB/SPCE (1st generation) | −0.30 | 0.25–2 | 10.0 | 17.0 | 72% after 45 days | [51] |
| GOx/Fc-COOH/SPCE (2nd generation) | +0.25 | 1–5 | 180.0 | 2.0 | ~80% after 3 weeks | [52] |
| GOx/DMFc/G (2nd generation) | +0.16 | 1–30 | 300 | - | - | [53] |
| GOx-SWCNTs-PVI-Os/SPCE (2nd generation) | +0.30 | 0.2–7.5 | 0.07 | 32 | ~90% after 30 days | [54] |
| CtCDH/GA/SWCNTs/SPCE (3rd generation) | +0.10 | 0.1–30 | 10.0 | - | ~90% after 7.5 h | [55] |
| CtCDH C291Y/GA/4-APh, 4-MBA/AuNPs/GC (3rd generation) | +0.25 | 0.02–30 | 6.2 | 3.1 | ~90% after 20 days | this work |