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. 2017 Jul 25;9(8):795. doi: 10.3390/nu9080795

Figure 6.

Figure 6

Unfolded protein response (UPR) is not activated in TauTKO hearts at an early age. Total lysates from 3-month-old WT and TauTKO mice treated with or without MitoTempo were subjected to western blot analysis of (A) phosphorylated PERK and ATF4 (B) spliced XBP-1 and phosphorylated-IRE1 and spliced XBP-1 and (C) GRP78. Each panel contains a representative gel and summation data expressed as means ± SEM of 6–9 hearts. Values are expressed relative to WT, where WT is fixed at 1.0. * p < 0.05.