Figure 1.

Body weight, food and water intake, and urine volume in PCS extract-treated, STZ-induced diabetic mice. Mice were injected with vehicle (Con) or STZ (50 mg/kg/day) for five consecutive days. STZ-induced diabetic mice (above 300 mg/dL blood glucose) were treated with vehicle (-), PCS extract (500 mg/kg/day), or losartan potassium (10 mg/kg/day) as a positive control for 8 weeks (n = 8–11/group). (A) Body weight after 8 weeks of treatment; (B) average water intake over 8 weeks; (C) average food intake over 8 weeks; and (D) urine volume for 24 h after 8 weeks of PCS extract treatment; †, p < 0.05 vs. Con mice. *, p < 0.05 vs. (-)/STZ mice.