Figure 3.

The effect of oral NaHCO₃ (1680 mg) administered prior to a high acid load meal on venous blood pH (A); pH iAUC (B); serum bicarbonate (C); and bicarbonate iAUC (D), with NaHCO₃ (solid circle) and placebo (hollow circle). Treatment was administered at t = −30 min and the meal completed at t = 0 (indicated by a dotted line). The effect of the treatment versus placebo on the postprandial outcome measure was tested by two-way repeated measure ANOVA and the difference in iAUC was tested by paired t-test, with p values indicated on the graphs. All data presented as mean ± standard error of the mean (SEM).