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. 2017 Aug 13;9(8):871. doi: 10.3390/nu9080871

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Percent changes in (a) Grip Strength and (b) Estimated Glomerular Filtration Rate (eGFR) were examined at one week and 1, 2, 4, 6, 8, 10, and 12 months after denosumab treatment. Percentage changes in bone mineral density (BMD) of (c) L1 to L4 lumbar vertebrae (L-BMD) and (d) bilateral total hips (H-BMD) at the first visit and at 4, 8, and 12 months. Results are expressed as the mean ± SE. ** p < 0.01, significant difference at one week or 1, 2, 4, 6, 8, 10, and 12 months compared with pre-treatment.