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Anti-inflammatory effects of NP histological analysis. Histological evaluation was performed by hematoxylin and eosin staining: (a) the control group; (b) the intraplantar CAR injection; (c,d) CAR with NP treatment and CAR with RP treatment, respectively; (a1–d1) low magnification of the respective panels; and (e) histological score for the various treatment groups. The figures are representative of at least three independent experiments. *** p < 0.001 vs. Sham; # p < 0.05 vs. CAR.
