Figure 3.

The effects of the significant covariates (P < 0.005, based on a likelihood ratio test) on the CD4 reconstitution of patients of 6 months, 12 months, 37 months (median age), and 5‐years‐old at the time of hematopoietic stem cell transplantation (HSCT). A typical individual is one who is not in each of the covariate groups listed. The expected curve of a healthy child uses the function for N(τ) given in the Methods section.2 Each other trajectory gives the effects of the significant covariates, included through the stepwise covariate model procedure. Conditioning drugs alemtuzumab (n = 158) and antithymocyte globulin (n = 10), and acute graft‐vs.‐host disease (n = 102) affect initial number of cells, whereas leukemia (n = 95) and having no conditioning (n = 41) affect long‐term reconstitution.