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Potential risk factors for vancomycin nephrotoxicity
| Vancomycin exposure variables | Loading dose |
| Total daily dose | |
| AUC | |
| Trough level | |
| Duration | |
| Continuous vs. intermittent infusion | |
| Patient‐specific factors | Obesity |
| Severity of illness | |
| ICU residence | |
| Chronic kidney disease | |
| Concurrent nephrotoxin exposure | |
| Concurrent aminoglycosides Concurrent piperacillin‐tazobactam |
