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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Curr Med Chem. 2016;23(18):1818–1869. doi: 10.2174/0929867323666160418114826

Fig. (6).

Fig. (6)

PET Time-activity curves in monkey brain regions after administration of [18F]FIMX. (A) At baseline; (B) after pre-block with a selective mGlu1 receptor antagonist; (C) at baseline with challenge from an mGlu1 receptor antagonist at 27.5 min; and (D) at baseline with challenge from an mGlu5 receptor antagonist at 27.5 min. (Adapted from [107]). The experiments show that [18F]FIMX has high specific binding to mGlu1 receptors at baseline.