Table 6.

Reports of BCRP transporter sensitivity for some PET radioligands in various species, based on in vitro assays and on in vivo, mainly PET, studies.

Radioligand	Imaging target	In vivo species	In vitro species	Substrate (Yes/No)	Reference
[¹⁸F]MPPF	5-HT_1A	M (g)		No	[194]
[¹⁸F]MPPF	5-HT_1A		H (c)	No	[197]
[¹¹C]WAY	5-HT_1A		H (c)	No	[197]
[¹¹C]PIB	A_β		H (c)	No	[197]
[¹¹C]Flumazenil	Bz		H (c)	No	[197]
[¹⁸F]Fallypride	D₂/D₃		H (c)	No	[197]
[¹¹C]Raclopride	D₂/D₃		H (c)	No	[197]
[¹¹C]Befloxatone	MAO-A	R (g)		No	[205]
[¹¹C]Befloxatone	MAO-A		H (c)	Yes	[197]
[¹¹C]PK11195	TSPO		H (c)	No	[197]

M = Mouse, R = Rat; H = Human.

c = cell-based assay; g = efflux transporter knockout.