Table 3.

Frequency and timing of administration of fentanyl and midazolam for treatment of emergence agitation^a following sevoflurane anaesthesia in children undergoing ophthalmic surgery, stratified by study drug.

Parameter	Midazolam group n = 34	Ketamine group n = 33
Total fentanyl dose		NS
0	21	23
1	4	6
2	9	4
Total midazolam dose		P = 0.042
0	30	33
1	4	0
2	0	0
Timing of doses after arrival in PACU
0–10 min
Fentanyl, one dose	3/4	4/6
Fentanyl, two doses	9/9	3/4
10–20 min
Fentanyl, one dose	1/4	2/6
Fentanyl, two doses	0/9	1/4
Midazolam, one dose	4/4	–
20–30 min	–	–

Data presented as n patients.

NS, not statistically significant (P ≥ 0.05; χ²-test).

PACU, postanaesthesia care unit.

^aAono’s four-point scale score ≥3.¹³