Table 1.
Demographic, clinical characteristics and tumor features of patients with malignant colorectal occlusion.
Outcomes | Totala (n = 177) |
SEMS (n = 85) |
Urgent surgery (n = 92) |
p Value |
---|---|---|---|---|
Demographic characteristics | ||||
Age (years), mean ± Standard deviation (range) | 70.5 ± 13.0 (34–95) | 73.3 ± 11.8 (46–95) | 68.0 ± 13.5 (34–91) | 0.006 |
Gender, n (%) | ||||
Male | 108 (61.0) | 53 (62.4) | 55 (59.8) | 0.726 |
Female | 69 (39.0) | 32 (37.6) | 37 (40.2) | |
Average BMI ± SD: kg/m2 (range) | 24.1 ± 5.0 (14.9–39.1) | 24.7 ± 4.8 (14.9–35.9) | 25.1 ± 5.1 (17.7–39.1) | 0.690 |
Clinical characteristics | ||||
Medical comorbidities, n (%)b | 122 (69.7) | 58 (59.0) | 64 (70.3) | 0.854 |
Hypertension | 91 (64.1) | 50 (67.6) | 41 (60.3) | 0.367 |
Diabetes Mellitus | 40 (31.7) | 25 (43.1) | 15 (22.1) | 0.011 |
Cardiovascular disease | 28 (22.2) | 19 (32.8) | 9 (13.2) | 0.009 |
Pulmonary disease | 14 (11.1) | 6 (10.3) | 8 (11.8) | 0.800 |
Renal disease | 10 (7.9) | 7 (12.1) | 3 (4.4) | 0.185 |
Gastrointestinal disease | 24 (19.0) | 9 (15.5) | 15 (22.1) | 0.351 |
ASA scoring, n (%) | 0.354 | |||
I | 12 (9.4) | 4 (10.5) | 8 (8.9) | |
II | 57 (44.5) | 21 (55.3) | 36 (40.0) | 0.049 |
III | 39 (30.5) | 8 (21.1) | 31 (34.4) | |
IV | 20 (15.6) | 5 (13.2) | 15 (16.7) | 0.066 |
Blood parameters, n (%) | ||||
Anemia (Hb < 13 g/dL – in men; Hb < 12 g/dL – in women) | 46 (39.7) | 12 (38.7) | 34 (40.0) | 0.010 |
Severe anemia (Hb <8 g/dL) | 13 (11.2) | 0 | 13 (15.3) | |
Leucocytosis (>10.000) | 32 (29.6) | 3 (13.6) | 29 (33.7) | |
CRP increase (>2.50 mg/dL) | 46 (74.2) | 9 (50.0) | 37 (84.1) | |
Tumor features | ||||
Location, n (%) | 0.001 | |||
Left colon | 146 (82.5) | 77 (90.6) | 69 (75.0) | |
Transverse colon | 14 (7.9) | 7 (8.2) | 7 (7.6) | 0.061 |
Right colon | 17 (9.6) | 1 (1.2) | 16 (17.4) | |
Type of occlusion, n (%) | 0.011 | |||
Complete | 113 (67.3) | 48 (60.0) | 65 (73.9) | |
Partial | 55 (32.7) | 32 (40.0) | 23 (26.1) | |
Dukes classification, n (%) | ||||
A | 1 (0.6) | 1 (1.2) | 0 | |
B | 54 (32.7) | 22 (26.8) | 32 (38.6) | |
C | 46 (27.9) | 18 (22.0) | 28 (33.7) | |
D | 64 (38.8) | 41 (50.0) | 23 (27.7) | |
Treatment purpose | 0.001 | |||
Curative, n (%) | 106 (59.9) | 35 (41.2) | 71 (77.2) | |
Palliative, n (%) | 71 (40.1) | 50 (58.8) | 21 (22.8) |
Total-group that underwent SEMS placement plus group that underwent urgent surgery.
More than one patient had more than one medical comorbidity.