Table 1.
Baseline characteristics of the study population and univariate associations with progression of hip osteoarthritis. Values are numbers (percentages) of participants unless otherwise indicated
| Study population (n=1904) | Odds ratio (95% CI) | |
|---|---|---|
| Women | 1005 (52.8) | 2.0 (1.6 to 2.6)* |
| Mean age in years (SD) | 66.2 (7.0) | 1.1 (1.1 to 1.1)* |
| Body mass index ≥30 kg/m2 | 240 (12.6) | 1.6 (1.1 to 2.2)* |
| Type 2 diabetes | 166 (8.7) | 0.9 (0.6 to 1.3) |
| Hypertension | 585 (30.7) | 0.9(0.7 to 1.1) |
| Family history of osteoarthritis | 244 (12.8) | 1.4 (1.0 to 2.0)* |
| Age at menopause (reference group >50): | ||
| ≤45 | 463 (24.3) Should these not add up to 1005 (52.8%) | 1.3 (0.9 to 1.9)* |
| 46-50 | 703 (36.9) | 1.6 (1.1 to 2.2)* |
| Heavy mechanical workload | 242 (12.7) | 0.8(0.5 to 1.1) |
| Presence of hip pain | 187 (9.8) | 3.4 (2.5 to 4.6)* |
| Lower limb disability | 255 (13.4) | 3.2 (2.5 to 4.3)* |
| Presence of morning stiffness | 571 (30.0) | 1.7 (1.3 to 2.2)* |
| Joint space width at baseline ≤2.5 mm | 145 (7.6) | 7.2 (5.2 to 9.9)* |
| Osteoarthritis on radiograph | ||
| Hip ≥grade 2 | 191 (10.0) | 8.9 (6.8 to 11.6)* |
| Grade 2 | 156 (8.2) | |
| Grade 3 | 27 (1.4) | |
| Grade 4 | 8 (0.4) | |
| Knee | 345 (18.1) | 1.0 (0.6 to 1.4) |
| Hand | 451 (23.7) | 2.0 (1.5 to 2.6)* |
Progression of the hip was defined as a joint space narrowing ≥1.0 mm or a total hip replacement at follow-up.
*
P<0.1