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. 2017 Sep 1;15:165. doi: 10.1186/s12916-017-0929-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Correlation of biological hallmarks with the radioresistance (RadR) score and their distribution with molecular subtypes in human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC). a The RadR score was correlated to the enrichment scores (ESs) of 48 hallmarks gene sets in 421, 179, and 82 HPV-negative HNSCC from TCGA, GSE65858, and GSE39366, respectively. The 14 hallmarks significantly (P < 0.05) correlated in all three datasets are shown. b ESs of hallmarks which were positively correlated to the RadR score were compared between the four molecular subtypes of HNSCC in the three datasets. At: atypical; Ba: basal; Cl: classical; Me: mesenchymal