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. 2017 Aug 31;17:601. doi: 10.1186/s12879-017-2697-x

Table 3.

Analysis of mutation in the BCP, precore/core gene reported to be associated with HCC in 135 HBV isolates from southern Vietnam

Nucleotide All isolates
N = 135% (n)
Genotype B
N = 98% (n)
Genotype C
N = 37% (n)
p value
Mutation in BCP region
 C1653T 0.7 (1) 1.1 (1) 0.0 (0) 0.726
 T1753C 11.1 (15) 1.1 (1) 37.8 (14) 0.000
 G1757A 7.4 (10) 0 (0) 27.0 (10) 0.000
 A1762T 25.9 (35) 10.2 (10) 76.6 (25) 0.000
 G1764A 24.4 (33) 8.2 (8) 76.6 (25) 0.000
 A1762T/G1764A 24.4 (33) 8.2 (8) 76.6 (25) 0.000
 C1766G 2.2 (3) 2.0 (2) 2.7 (1) 0.621
 T1768A 1.4 (2) 1.1 (1) 2.7 (1) 0.475
Mutation in PC/Core
 G1896A 22.2 (30) 30.6 (30) 0 (0) 0.000
 G1899A 0.7 (1) 1.1 (1) 0 (0) 0.726
 A2159G 3.7 (5) 3.1 (3) 5.4 (2) 0.419
 A2189C 6.7 (9) 6.1 (6) 8.1 (3) 0.469
 G2203A/T 0.7 (1) 1.0 (1) 0.0 (0) 0.726