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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Cell Rep. 2017 Aug 29;20(9):2116–2130. doi: 10.1016/j.celrep.2017.08.014

FIGURE 2. Reduced survival and variable expressivity of Apela mutants.

FIGURE 2

(A–B) Affected Apela NEO-IN (A) and NEO-OUT (B) null phenotypes at E9.5 and E10.5. Pooling of blood in the YS and embryo in affected mutants (green arrowheads). (C) Penetrance of affected Apela null phenotypes (scored according to YS remodeling) was 9–11% at E9.5. Genotype of the mother did not impact penetrance of affected Apela null phenotypes. (D) Recovery of Apela null embryos at E9.5, E10.5, and E15.5. FB, forebrain; PE, pericardial edema.