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. 2017 Sep 1;17:610. doi: 10.1186/s12885-017-3629-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Analysis of GPR155 expression in clinical specimens. a There were no significant differences in GPR155 mRNA levels among non-cancerous tissues categorized by background uninvolved liver status. b GPR155 mRNA was expressed at lower levels in HCC tissues compared with corresponding non-cancerous tissues. c Correlation of GPR155 mRNA expression levels in HCC tissues with preoperative serum α-fetoprotein levels. d Detection of GPR155 protein in two representative patients. In both cases, cancerous tissues exhibited reduced expression compared with adjacent non-cancerous tissues (100× and 400× magnification). N, non-cancerous component; T, tumor component. A significant correlation between staining intensity and transcription patterns of GPR155 was observed