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. 2017 Sep;24(9):392–399. doi: 10.1101/lm.045724.117

Figure 3.

Figure 3.

The CFC “null point” does not result from individual differences. Animals were subjected to contextual fear conditioning in big cohorts and 2 d later, to an intermediate reexposure session of 10 or 5 min. Immediately after, they received i.p. MK-801 or Saline and on the following day, memory was assessed in a test session. Freezing percentages during the test session were then correlated to (A) freezing at the end (last 3 min) of the 10-min reexposure session, (B) freezing at the start (first 3 min) of the 10-min reexposure session, (C) decline of freezing during the 10-min reexposure session (start–end), (D) freezing at the end (last 2 min) of the 5-min reexposure session, (E) freezing at the start (first 3 min) of the 5-min reexposure session, (F) decline of freezing during the 5-min reexposure session (start–end). A, D, and E show significant correlations between parameters for both Sal and MK-801 groups (P < 0.05). MK-801 did not significantly affect the slopes or the intercepts of any significant regressions. Data presented as mean + SEM. n = 19–21 per group.