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. 2017 Sep;27(9):1589–1596. doi: 10.1101/gr.210666.116

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© 2017 Legrand et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 2. — WTBS of mouse ES cell mRNA. (A) Frequency of bisulfite nonconversion (resp. methylation) ratios in mRNA. (B) Estimated Poisson rate λ_p/coverage as a function of coverage, as well as corresponding boxplot. (C) Bisulfite nonconversion ratio (x-axis) and −log of methylation P-values (y-axis) for 53,510 cytosines passing the 0.2 ratio threshold. Color indicates density (count of points per symbol area). (D) Cytosine position and methylation tracks for a representative mRNA transcript (NM_007984) in three replicates.