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. 2017 Sep;27(9):1589–1596. doi: 10.1101/gr.210666.116

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© 2017 Legrand et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 6. — Site-specific methylation analysis by whole-transcriptome bisulfite sequencing. Scatter plots show nonconverted cytosines for tRNA (A), rRNA (B), and mRNA (C) in wild-type and Dnmt2 knockout ES cells. Methylation ratios are specifically reduced for C38 of tRNA(Asp), tRNA(Gly), and tRNA(Val) in Dnmt2 knockouts. (D) Scatter plot for mRNA in wild-type and TET-deficient ES cells.