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. Author manuscript; available in PMC: 2017 Dec 19.
Published in final edited form as: Nat Chem Biol. 2017 Jun 19;13(8):902–908. doi: 10.1038/nchembio.2413

Figure 4. Curli originate from one-step, direct nucleation events.

Figure 4

(a) AFM monitoring of nucleation and growth of CsgA fibers in situ (see also Supporting Video 1; vertical deflection channel); (b) Following single fiber nucleation using high speed AFM (error signal): new fiber fragments form seemingly unprompted and have lateral dimensions that are identical to mature, single fibers (see also Supporting Video 2). In both panels, separate fibers are indicated in a different color, with pre-nucleation events encircled with a dashed line (I) and the consecutive events indicated by II and III.