Figure 4.

Social stress induces anxiety with individual variability. Individual data of the time spent in the interaction zone (interaction time, (a)) and social interaction (SI) ratios (b) in control mice (n = 6) and in mice treated with social defeat stress (SDS, n = 9). Averaged data of SI ratios (c) and interaction time (d) in control mice (n = 6) and in stressed mice of susceptible group (SI ratio < 1, n = 5) and of resilient group (SI ratio > 1, n = 4). Individual data of central times (e) and total distance traveled (f) in the control mice (n = 6) and in the susceptible (n = 5) and resilient (n = 4) groups of stressed mice defined above in OFT.

SDS: social defeat stress; SI: social interaction.