Figure 3.

Effect of OHS extract on tail flick test (A) and acetic acid-induced vascular permeability (B). To perform tail flick test, rats were placed over tail flick unit. Rats’ tail was adjusted in the flush mounted window. Then, IRI energy was passed and the time to flicking was measured. For vascular permeability test, the amount of Evans blue leakage in the abdominal cavity was measured as an indicator of inflammation degree. Control, vehicle (water) treated group; OHS100, treated with OHS extract of 100 mg/kg body weight; OHS200, treated with OHS extract of 200 mg/kg body weight. Codeine 10 mg/kg was used as a positive control. Data are representative of three independent experiments (mean and SEM). One-way ANOVA. *p<0.05; ***p<0.001; ****p<0.0001