Table 1.
Effect of OHS extract on serotonin-induced paw edema test
| Group |
Swelling thickness ( 10
-3
ml)
|
|||||
|---|---|---|---|---|---|---|
| 6 min | 12 min | 18 min | 24 min | 30 min | ||
| Control | 6.3±0.05 | 12.8±0.06 | 19.3±0.08 | 26.9±0.05 | 21.8±0.04 | |
| OHS100 | 6.2±0.04*** | 12.2±0.08**** | 18.7±0.05**** | 25.3±0.03**** | 20.6±0.04**** | |
| OHS200 | 6.0±0.04**** | 12.1±0.08**** | 18.6±0.06**** | 24.6±0.05**** | 19.3±0.04**** | |
| Indomethacin | 5.4±0.04**** | 10.9±0.04**** | 13.6±0.04**** | 15.9±0.03**** | 12.8±0.03**** | |
Data are representative of three independent experiments (mean and SEM). One-way ANOVA.
***
p<0.001;
****
p<0.0001. Indomethacin (10 mg/kg body weight) was used as a positive control.